Welcome to the Lile Wellness Partners Library! We have put together articles from medical professionals on a variety of topics to help our patients better understand the complexities of health care.
Feel free to peruse the library and “check out” any articles of interest to you. We’ll update the library from time to time, as well as posting our thoughts on health news on our blog.
A new study provides the strongest evidence that anticholinergic drugs may increase the risk for dementia in older adults.
As people age, the brain takes longer to clear amyloid-13, which may explain why risk for the disease increases with age, researchers say.
Age-related memory decline may be reversed with high doses of naturally occurring cocoa flavanois, US researchers have discovered in findings that establish the dentate gyrus as central to cognitive decline.
A new study finds an association between type 2 diabetes and a lower risk for amyotrophic lateral sclerosis (ALS), while type 1 diabetes was associated with a higher risk.
Dietary changes that reduce the incidence of, and prevent, mental health disorders are a cost-effective and efficacious means of improving mental health, urges a position statement that sets out a series of recommendations to advance nutritional medicine in psychiatry.
In the first study of its kind, Danish researchers have shown that intensive aerobic exercise has a positive cognitive effect in patients with Alzheimers’s Disease(AD).
Alterations in fatty acid (FA) metabolism and the way it is regulated by cortisol may be linked to response to antidepressant treatment in patients with major depressive disorder (MDD). In addition, increasing fatty fish intake may “boost” treatment response, new research suggests.
Eating fish may protect against depression, a new meta-analysis suggests.
Higher consumption of green tea was associated with a lower risk for dementia or mild cognitive impairment (MCI), even after possible confounding factors were considered, a Japanese study shows. Black tea or coffee did not show the same effect.
Herpes simplex virus infection appears to double the risk of developing Alzheimer’s disease {AD), claim Swedish researchers in two separate studies.
Measuring cortisol in saliva may help identify healthy older people with cognitive impairment, a new study hints.
A diet considered high in quality according to a healthy eating index preserves cognition in patients at high risk for cardiovascular disease and mental decline, results of a new study suggest.
Higher intake of trans fat, commonly used in processed foods to improve taste, texture, and shelf life, has been linked to worse memory function in men in their prime earning years.
The MIND diet – a hybrid of the Mediterranean diet and the Dietary Approaches to Stop Hypertension (DASH) diet – may slow cognitive decline in elderly adults, according to researchers from Chicago’s Rush University Medical Center who developed the MIND diet.
New research has suggested that migraine may be associated with irregularities in the metabolism of certain lipids, opening up new avenues for research into possible treatments and biomarkers for the condition.
Reaction has continued to grow regarding the November 2013 JAMA article, “Association of Testosterone Therapy With Mortality, Myocardial Infarction, and Stroke in Men With low Testosterone Levels.” Here are some of the recent developments.
Low levels of oxygen saturation during sleep and reduced durations of slow-wave sleep are both associated with more brain pathology characteristic of dementia, a new study shows.
Low vitamin D levels are very common in older adults, especially African Americans and Hispanics, and are associated with accelerated decline in episodic memory and executive function, the two cognitive domains strongly associated with Alzheimer’s disease (AD) dementia, a new study indicates.
Compared with healthy controls, women with multiple sclerosis (MS) have lower levels of folate, magnesium, vitamin E, and other nutrients that may have important anti-inflammatory or antioxidant properties, a new study shows.
Small trial by UCLA and Buck Institute succeeds using ‘systems approach’ to memory disorders.
A modified Atkins diet (mAD) can decrease seizures in adult patients with refractory epilepsy taking antiepileptic drugs (AEDs).
Women between 50 and 69 years of age who participate in screening mammography have about a 40% reduction in the risk for death from breast cancer, an update from the International Agency for Research on Cancer (!ARC)Working Group concludes.
Who would have imagined that the same diet that heals heart disease may also heal MS? Indeed, the dietary therapy that has been studied with the greatest efficacy and duration for MS is a predominantly plant based diet low in fat, called the Swank Diet.
Researchers have identified a new gene involved in the immune system that increases the risk for Alzheimer’s disease (AD), providing a potential new target for prevention and treatment.
Nine potentially modifiable risk factors may explain two-thirds of Alzheimer’s disease (AD) cases globally, according to a comprehensive meta-analysis of published studies.
A novel, comprehensive lifestyle intervention has shown promise in reversing memory loss related to Alzheimer’s disease (AD), preliminary research suggests.
Shooting at the same target but with a different kind of arrow, Chinese researchers have shown that an oligosaccharide that binds more than one region of amyloid-ß (Aß) enhances clearance of the protein from the brain and improves cognition among patients with mild to moderate Alzheimer’s disease (AD).
High-dose oral resveratrol (RES) administration stabilized levels of amyloid-beta -40 (Aß40) in cerebrospinal fluid (CSF) and plasma compared with placebo in patients with mild to moderate Alzheimer’s disease (AD), a phase 2 study shows.
Individuals who are overweight or obese and those who do not engage in physical activity have an increased risk for meningioma, a new systematic review of the literature suggests.
Intranasal administration of oxytocin twice daily for 1 week was safe and well tolerated and showed preliminary signs of improvement in symptoms of apathy and loss of empathy in patients with frontotemporal dementia, according to a new study.
Oxytocin…It’s not just about sex! Top Ten Effects of Oxytocin in Humans…
A single, brief session of resistance exercise done immediately after a visual learning task enhances episodic memory by about 10%, new research shows.
A novel new study supports a causal role for low vitamin Din risk for multiple sclerosis (MS), researchers say.
A dispute has raged for 70 years as to whether or not maturing women should replace their sex hormones. The age-reversal impact of hormone replacement is quite noticeable. As a result, many women want to stay on their hormones for life.
Suzanne Somers has been dubbed a health “pioneer” by Oprah Winfrey and been told by Dr. Mehmet Oz that she is “crazy smart.” She is the author of twenty-four books and has appeared on hundreds of national broadcasts to discuss her cutting-edge views on how medicine should be practiced. The Wall Street Journal says she writes with “the passion of a prophet.”
Older people with type 2 diabetes have an elevated level of tau protein in their cerebrospinal fluid (CSF) whether they have normal cognition, mild cogryitive impairment (MCI), or dementia, a new study has shown.
Adults 50 to 69 years of age should take daily low-dose aspirin for at least 10 years to reduce their risk for cardiovascular disease (CVD) and co)orectal cancer, according to a set of draft recommendations from the US Preventive Services Task Force (USPSTF).
Consumption of an unhealthy Western diet characterized by meat, hamburgers, chips, and soft drinks, may reduce the volume of the left hippocampus, whereas a healthy diet of fresh vegetables and fish may increase hippocampal volume.
A new study supports a link between low levels of vitamin D and increased risk for cognitive decline, prompting calls for clinical trials to test whether vitamin D supplementation may delay or prevent dementia.
Vitamin C has been found to cut the risk of premature death from cancer, cardiovascular disease, and weakened immune function. In a recent study, people with the highest blood levels of vitamin C demonstrated a 25% lower risk of dying from any cause.
Colonoscopy reduces cancer risk and mortality in patients with inflammatory bowel disease, according to the largest study of its kind, presented here at the American College of Gastroenterology (ACG) 2014 Annual Scientific Meeting.
An inflammatory component is present in the microenvironment of most neoplastic tissues. Inflammation and elevated C-reactive protein (CRP) are associated with poor prognosis and decreased survival in many types of cancer.
Scientists have found that high intravenous doses of vitamin C kills cancer cells. The ascorbate dose has to be very high, too high to be taken orally, hence the intravenous administration. Some recent trials showed orally administered vitamin C had no effect on cancer cells, so the researchers decided to see what would happen if they injected the ascorbale straight into the bloodstream.
Athough findings that a healthy diet is good for the heart aren’t really a surprise anymore, new research suggests that this may be because of the increase in vitamin-C levels that come from a high intake of fruit and vegetables.
Lab study found it also left healthy cells unharmed, but experts say more research needed.
Researchers have confirmed that nicotinamide plays a significant role in producing ATP, which facilitates DNA repair in skin cells damaged by solar radiation.
Prediabetes – even at lower levels of impaired fasting glucose (IFG) as defined by the American Diabetes Association (ADA) – is associated with a significant increase in cancer risk that is independent of the effects of obesity, according to the results of a large new meta-analysis.
Taurine (Tau) has been shown to possess cancer therapeutic effect through induction of apoptosis, while the underlying molecular mechanism of its anti-cancer effect is not well understood.
There’s a lot of confusion out there when it comes to the topic of progesterone and breast cancer. Many women worry when they hear that their breast cancer is both ER+ and PR+, believing this to be “double trouble”. It is time to set the record straight.
Vegetarians appear to be at lower risk for colorectal cancer than nonvegetarians, new research shows.
The notion that food items could slow or even reverse atherosclerosis of heart arteries, one of the most serious health threats in the Western world, was considered unlikely until demonstrated by the LifeStyle Heart Trial decades ago.
Thresholds for electrically induced atrial fibrillation were measured in response to IV carnitine.
Mean arterial pressure, heart rate, and mean aortic flow rate were also monitored. Carnitine 100 mg/kg resulted in an increase in mean aortic blood flow. The antiarrhythmic effect was much less than with 5 mg/kg quinidine, but after atropinization, 100 mg/kg carnitine was similar in antiarrhythmic effect to quinidine and did not result in the blood pressure depression seen with quinidine.
Scientists at the University of Virginia have linked high levels of C-reactive protein with an increased risk of ischemic stroke.
In a study of 18-to-45-year-olds with untreated stage 1 hypertension, “moderate coffee drinkers” who drank one to three espressos a day were three times as likely to have a CV event (mostly a heart attack) within a decade as those who did not drink toffeeI 1l.
Diet rich in foods with antioxidants appears to provide protection against the development of atrial fibrillation (AF) following cardiac surgery, according to the results of a new observational study(1).
Consuming more whole-grain foods was linked with a decreased risk of dying, mainly from cardiovascular disease (CVD), but not from cancer, in a long-term study of more than 100 000 American healthcare professionals.
We searched for nutrient deficiencies that could cause cardiac arrhythmias [premature atrial contractions (PACs), premature ventricular contractions (PVCs), atrial fibrillation, and related sinus pauses], and found literature support for deficiencies of taurine and I-arginine.
The September 2015 issue of Asia Pacific Journal of Clinical Nutrition published the finding of researchers at Zhejiang University in China of a reduction in plasma homcysteine levels following supplementation with vitamin B12 and/or fish oil.
A low-carbohydrate diet may be better than a low-fat diet for losing weight and reducing risks for cardiovascular disease (CVD), according to an article published in the September 2 issue of Annals of Internal Medicine.
Rejoice, chocolate lovers: more findings suggest that regular consumption of the sweet stuff may decrease the risk of CV events and stroke in otherwise healthy individuals.
“We have stalled in the fight against heart disease,” Dr. Kahn says. “We aren’t addressing many of the underlying causes of heart disease. The current model is not addressing nutrition, supplements, or lifestyle.”
To investigate the association between long term intake of dietary and supplemental calcium and death from all causes and cardiovascular disease.
Long-term testosterone replacement therapy is associated with a decreased-not increased-risk for cardiovascular disease in men, according to a large population-based cohort study published online May 7, 2016, in “Lancet Diabetes & Endocrinology”.
People with ischemic heart disease have a lower bone-mineral density (BMD) of the wrist, according to a recent study using a new scanning technology that shows a link between cardiovascular disease and bone loss. The study was published in the July issue of Osteoporosis International.
New research suggests it’s important for patients’ cardiovascular health not only to cut saturated fats from their diets but to trade them out for high-quality carbohydrates and/or unsaturated fats-especially polyunsaturated fatty acids (PUFA)
As documented in the popular press and in a growing body of clinical research, sitting for long stretches of time is now considered to be as dangerous as smoking, with many health experts urging the population at large to stand up and get moving, or at the very least, to just stand up.
A reduction in the consumption of added sugars and, in particular, processed foods may translate into decreased rates of hypertension as well as decreased cardiometabolic disease. In particular, a new review article suggests that sugar, not salt, appears to contribute to the majority of the hypertension risk associated with processed food.
White race is associated with a substantially higher risk of incident atrial fibrillation (AF) compared with blacks, and systemic inflammation contributes to a significant proportion of that heightened risk, the Health ABC (Health, Aging and Body Composition) study, published in the August 2015 issue of JACC: Clinical Electrophysiology, suggests.
Taurine is an organic osmolyte involved in cell volume regulation and provides a substrate for the formation of bile salts.
Prolonged sitting was associated with higher mortality from all causes, as well as increased incidence of cancer, cardiovascular disease, and type 2 diabetes, even among people who exercise regularly, according to a meta-analysis published in the January 20 issue of the Annals of Internal Medicine.
Each added hour spent sitting was associated with a 14% increase in coronary artery calcium (CAC) score, independent of traditional risk factors, including physical activity, in a study of middle-aged subjects without cardiovascular disease.
Adults 50 to 69 years of age should take daily low-dose aspirin for at least 10 years to reduce their risk for cardiovascular disease (CVD) and colorectal cancer, according to a set of draft recommendations from the US Preventive Services Task Force (USPSTF).
Metformin activates AMPK which has broad-ranging effects that not only lowers blood sugar but can prevent, and even reverse, the life-shortening effects of aging, such as cardiovascular disease, diabetes, neurodegenerative diseases, cancer, and more.
A new study suggests an aging gut microbiome may be somewhat responsible for the degradation in cardiovascular heath that tends to appear as we grow older. The study is yet another addition to the growing body of evidence affirming the role gut bacteria plays in age-related disease.
Both initial and sustained responses to fecal microbiota transplant (FMT) for the treatment of refractory C difficile infection remain high out to 18 months’ follow-up, provided patients do not require antibiotics for the treatment of an unrelated infection, new research shows.
People who take multiple courses of antibiotics may face an increased risk of developing both type 1 and type 2 diabetes, potentially through alterations in gut microbiota, conclude US researchers.
Probiotic bacteria exhibit a variety of properties, including immunomodulatory activity, which are unique to a particular strain. Thus, not all species will necessarily have the same therapeutic potential in a particular condition. We have preliminary evidence that Bifidobacterium infantis 35624 may have utility in irritable bowel syndrome (IBS).
Fecal microbiota transplantation successfully decolonized the gut of a young girl who persistently harbored multidrug-resistant Klebsiella pneumoniae bacteria, according to a case report.
At first glance, fecal microbiota transplant (FMT) appears more like gardening than clinical medicine, involving as it does the “replanting” of normal microorganisms into the gastrointestinal tract.
However, FMT’s nearly 90% cure rate for patients with recurrent Clostridium difficile infection (COi) verifies its surprising new role in contemporary gastroenterology-namely, as the most effective treatment available for this indication, far surpassing that of antibiotics. The success of FMT has catalyzed a surge of new approaches to replacing gut microbes and a dramatic revision to the US Food and Drug Administration’s (FDA) initial regulatory approach.
Researchers in Finland have discovered what could be an important clue to what drives Parkinson’s disease (PD). Their new study has shown a reduced abundance of the Prevotellaceae bacteria family in the gut microbiome of PD patients compared with healthy persons.
Decreased gut microbial diversity is strongly associated with high body mass index (BMI) and triglyceride levels, as well as a low level of high-density lipoproteins (HDL), according to results of the first study to determine how the gut microbiome relates to body weight arid blood lipids.
Gut microbes may be a key link between jet lag and obesity, according to research done in mice and confirmed in two humans. Mice whose daily rhythms were disrupted showed changes in the populations of bacteria in their gut and gained weight more easily on a high-fat diet than did mice whose rhythms remained stable.
Yale School of Medicine recently published a report showing that Leukocyte Activation (LA) testing identifies food items that induce a patient specific cellular response in the immune system, and has also recently been shown in a randomized double blinded prospective study to reduce symptoms in patients with irritable bowel syndrome.
Analysis of the microbiome surrounding colon cancer tumors could be used as a noninvasive screening test that is more sensitive and specific than fecal occult blood testing, according to the results of a new study.
Good news, men: you may be able to decrease your risk for prostate cancer by ejaculating – frequently, according to research presented here at American Urological Association 2015 Annual Meeting.
There is no consistent evidence that the use of testosterone in men with hypogonadism increases the risk for cardiovascular problems, according to a new review by the Pharmacovigilance Risk Assessment Committee (PRAG) of the European Medicines Agency (EMA).
This article describes novel curative procedures along with natural methods to prevent and reverse low-grade prostate disease.
Long-term testosterone replacement therapy is associated with a decreased-not increased-risk for cardiovascular disease in men, according to a large population-based cohort study published online May 7, 2016 in “Lancet Diabetes & Endocrinology”.
In a cross-sectional study of men around 60 years old with type 2 diabetes, those with low total plasma testosterone levels had a sixfold higher risk for increased carotid artery intima media thickness (CIMT) and decreased endothelial function, compared with their peers with normal testosterone.
Low levels of vitamin D are significantly and independently associated with low levels of testosterone in otherwise healthy middle-aged men, according to a study presented at the American Urological Association 2015 Annual Meeting in New Orleans.
This article describes a physician/scientist who has spent decades perfecting a minimally invasive diagnostic and treatment approach that may revolutionize conventional prostate cancer treatment.
The March 2016 issue of the European Journal of Endocrinology published a meta-analysis of randomized trials and observational studies that affirmed an association between testosterone supplementation and improvement in body composition, glucose levels and insulin resistance.
A number of natural extracts have proven value in preventing, and often reversing, symptoms of benign prostatic hyperplasia and chronic prostatitis with a high safety profile. There is also evidence that certain supplements can help prevent prostate cancer, and even slow the rate of cancer progression if it does occur.
Two new studies muddy the waters on the potential cardiovascular risks previously linked to testosterone-replacement therapy in men, with both studies suggesting the therapy might not be causing the cardiovascular harm suggested in previous analyses. Both are scheduled for the presentation later this week at the American College of Cardiology (ACC) 2015 Scientific Sessions.
Contrary to recent findings, a new retrospective study of data from 40 specialized clinics around the United States has found that testosterone therapy in men is not associated with an increased risk for myocardial infarction (Ml) or stroke and may even be cardioprotective.
Testosterone levels are high in young men, but plummet during aging.
Contrary to recent findings, a new retrospective study of data from 40 specialized clinics around the United States has found that testosterone therapy in men is not associated with an increased risk for myocardial infarction (Ml) or stroke and may even be cardioprotective.
Testosterone replacement Not Linked to Blood Clots. A study conducted by researchers at The University of Texas.
An article appearing on May 27, 2016 in BJU International reveals better sexual function in men with type 2 diabetes with severely depressed hormone levels who were treated with testosterone undecanoate.
Older men with low or low-normal testosterone who received testosterone gel daily for 3 years did not have a faster progression of subclinical atherosclerosis compared with their peers who received placebo gel, in a new study. However, the testosterone-treated men also did not report any improved sexual function or health-related quality of life.
Epidemiological studies have found that men with low or low normal endogenous testosterone are at an increased risk of mortality than those with higher levels. Cardiovascular disease accounts for the greater proportion of deaths in those with low testosterone.
Results of a recent analysis of 231,408 medical records has failed to find an association between testosterone replacement therapy and an increased risk of prostate cancer.
Regular movement has real benefits for your health, longevity, and performance. Surprisingly, though, it isn’t about how much you exercise!
Eating just 2 large meals a day, consisting of breakfast and lunch, could be the best way for people with type 2 diabetes to help control their weight and their blood sugar, new research suggests.
Another study showing an increased risk for cancer with drinking alcohol, even with just one or two drinks a day, has prompted renewed warnings on the health risks associated with alcohol consumption.
Antibiotic use was associated with an increased risk for type 2, diabetes in a new population-based, case-control study.
A compound called berberine is one of the most effective natural supplements available. Berberine has been shown to lower blood sugar, cause weight loss and improve heart health. This is a detailed review of berberine and its health effects.
Sulforaphane, a compound found in broccoli sprouts, may improve core symptoms of autism spectrum disorder (ASD), preliminary research suggests.
The bulk of the evidence does not support guidelines that recommend a minimum calcium intake, including those from the Institute of Medicine, according to the authors of two new systematic reviews and meta-analyses.
Individuals who take more than 800 mg of calcium daily are almost twice as likely to be diagnosed with age related macular degeneration (AMD) as those who did not, according to the results of a new study published online April 9 in JAMA Ophthalmology.
Discover how DASH can improve your health and lower your blood pressure. The DASH diet encourages you to reduce the sodium in your diet and eat a variety of foods rich in nutrients that help lower blood pressure, such as potassium, calcium and magnesium.
Employees in predominantly desk-based occupations should be swapping their seats for their feet and accumulating 2 hours a day of standing and strolling walking during working hours, and eventually that should progress to 4 hours daily, according to a consensus statement published on line June 1 in the British Journal of Sports Medicine.
A large, cross-sectional Korean study has linked prolonged sitting and decreased physical activity with nonalcoholic fatty liver disease (NAFLD), even in physically active people of normal weight. The results, published online September 15 in the Journal of Hepatology, underscore mounting evidence of the importance of reducing sedentary time and increasing physical activity to prevent chronic illnesses and premature death.
Regular consumption of sugared beverages is associated with ‘a greater prevalence of fatty liver disease, even after adjusting for body mass index, according to a large observational study.
Swedish researchers have found that a high intake of milk may be associated with higher mortality and fracture risks in women and higher mortality risk in men, but they caution against basing any dietary recommendations on their findings, which were published online October 28 in BMJ.
“We’re seeing improvements in body weight and body fat percentage,” researcher Ann Brown, from Florida State University in Tallahassee, told Medscape Medical News.
Metformin was prescribed for only 3. 7% of patients with prediabetes, even though it can help prevent the onset of type 2 diabetes, according to a new retrospective cohort analysis.
Exposure to pesticides significantly increases the risk of type 2 diabetes by nearly 60%, finds an extensive literature review presented at the the European Association for the Study of Diabetes 2015 Meeting last week.
ProLon®- clinically studied to help your patients improve their health and aging.
Trading 2 minutes/hour of sedentary activity with light-intensity activity was linked to 33% lower mortality in the general population and 41 % lower mortality in those with chronic kidney disease (CKD), according to an observational analysis published on line April 30 in the Clinical Journal of the American Society of Nephrology.
Today I would like to talk about a small revolution that’s brewing in the dietary recommendations for the American population. An expert panel has released its new recommendations to the US Departments of Health and Human Services and Agriculture, which will draft the final US dietary guidelines later this fall. [‘l Those guidelines, which are updated every 5 years, will likely no longer set an upper limit for cholesterol intake for people with hypercholesterolemia.
Metformin activates AMPK which has broad-ranging effects that not only lowers blood sugar but can prevent, and even reverse, the life shortening effects of aging, such as cardiovascular disease, diabetes, neurodegenerative diseases, cancer, and more.
Eating a plant-based diet rich in fruits, vegetables, and nuts and low in animal fats, dairy, and sweets can reduce the risk for stroke by up to 18% compared with a less healthy dietary pattern, a new study suggests.
A new analysis suggests yet another potential health benefit of the Mediterranean diet. In the Nurses’ Health Study, greater adherence to the Mediterranean diet was associated with greater telomere length, a biomarker of aging.
This guide is property of The Plantrition Project. This handbook, along with additional plant-based nutrition resources, can be downloaded at http://plantricianproject.org/quickstartguide.
While you are probably aware that plant-based diets have been shown to prevent and reverse heart disease, new research points to a host of other positive effects on other common diseases.
Is a yoga mat, a good nights sleep, and and plant-based lifestyle the fountain of youth? A new book by Nobel Prize laureate Elizabeth Blackburn, Ph.D., The Telomere Effect, suggests that the science indicates that this may be the case.
A collection of Theracurmin Research and Clinical Trials.
In this piece, renowned cardiologist Dr. Joel Kahn shares what you need to know about eating for optimal heath.
Maybe you already believe in the idea that “you are what you eat.” Now, Joel Kahn, M.D. looks at a powerful new study that takes that idea a step further, suggesting that the health of our planet is also what we eat.
If your thyroid is running a bit slow, a few changes in your diet may help to naturally bring back that bounce in your step.
Hellenic Journal of Nuclear Medicine published the finding of Greek researchers of an association between low serum vitamin D levels and an increase in a marker of the autoimmune disease known as Hashimoto’s thyroiditis (HT).
Studies show that taking thyroid medication at bedtime could be better.
A pooled analysis published on April 6, 2016 in PLOS ONE found an association between a substantial reduction in invasive cancers and higher vitamin D levels.
Higher levels of vitamin D were associated with “markedly” improved survival in patients with advanced colorectal cancer in a prospective study of more than 1000 patients.
Vitamin D supplementation augments the benefits of weight loss on systemic inflammation linked to cancer and chronic disease, according to new research.
Low serum levels of vitamin D are associated with clinically significant symptoms of depression in otherwise healthy individuals, new research shows.
Vitamin D supplementation prevented moderate to severe exacerbations of chronic obstructive pulmonary disease (COPD) in patients with vitamin D deficiency in a multicenter, double-blind, randomized controlled trial. The results were published online December 2 in the Lancet.
Hellenic Journal of Nuclear Medicine published the finding of Greek researchers of an association between low serum vitamin D levels and an increase in a marker of the autoimmune disease known as Hashimoto’s thyroiditis (HT).
The relative safety of bioidentical hormone replacement compared with traditional synthetic and animal-derived versions, such as conjugated equine estrogens (GEE), medroxyprogesterone acetate {MPA), and other synthetic progestins is the subject ofintense debate.
There is now convincing evidence that usual hormone therapy for ovarian failure increases the risk for breast cancer. We have previously shown that ovarian androgens normally protect mammary epithelial cells from excessive estrogenic stimulation, and therefore we hypothesized that the addition of testosterone to usual hormone therapy might protect women from breast cancer.
A cross-sectional survey was conducted to examine quality of life (QOL) related to physiological, somatic, and vasomotor effects of changing progestogen treatment from medroxyprogesterone acetate (MPA) to micronized progesterone in postmenopausal women. Eligible women (n = 176) were currently using hormone replacement therapy (HRT) containing micronized progesterone for 1,6 months and had previously received HRT containing MPA.
To review research findings on the effects of estrogen on cognition, mood, memory, and degenerative brain disease in women.
To assess pairwise differences between placebo, unopposed estrogen, and each of three estrogen/progestin regimens on selected heart disease risk factors in healthy postmenopausal women.
Coronary artery calcium, a radiographic marker for atherosclerosis and a predictor of coronary heart disease (CHO), is less extensive in women than in men of the same age. The role of estrogen in the pathogenesis of coronary artery calcification is unknown. We examined the association of estrogen status with extent of calcification and atherosclerotic plaque in coronary arteries of deceased women.
Middle-aged women who exercise regularly report a higher quality of life and reduced symptoms of menopause, according to a population-based study published in the January 2015 issue of Maturitas.
A combination of low-risk lifestyle factors substantially reduces the risk for stroke, particularly cerebral infarction, in women. In addition, there appears to be a progressive reduction in risk with more low-risk lifestyle factors adopted, new research suggests.
A new study finds that women who took hormone replacement therapy back in the 1990s are no more likely to die decades later than women who were given sugar pills.
If you are thinking about taking Hormone Replacement Therapy (HRT) or wondering if you should be coming off it, or going back on to it, you will be aware that there continues to be debate about its safety.
An accumulating body of evidence clearly establishes that estradiol is a potent neuroprotective and neurotrophic factor in the adult: it influences memory and cognition, decreases the risk and delays the onset of neurological diseases such as Alzheimer’s disease, and attenuates the extent of cell death that results from brain injuries such as cerebrovascular stroke and neurotrauma.
Women between 50 and 69 years of age who participate in screening mammography have about a 40% reduction in the risk for death from breast cancer, an update from the International Agency for Research on Cancer Working Group concludes.
Nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to inhibit ovulation and reduce progesterone levels in young women, which could seriously undermine fertility, new research suggests.
We sought to compare the effects of estrogen/transvaginal progesterone gel with estrogen/medroxyprogesterone acetate (MPA) on exercise-induced myocardial ischemia in postmenopausal women with coronary artery disease or previous myocardial infarction, or both.
Oxytocin…It’s not just about sex! Top Ten Effects of Oxytocin in Humans..
A report appearing on September 15, 2016 in the journal PLOS Pathogens describes a role for the hormone progesterone in reducing inflammation and improving lung function following infection with influenza.
Controlled studies and most observational studies published over the last 5 years suggest that the addition of synthetic progestins to estrogen in hormone replacement therapy (HRT), particularly in continuous-combined regimen, increases the breast cancer (BC) risk compared to estrogen alone.
Progestogens are clearly useful to balance the proliferative effects of estrogens on the endometrium; however, some progestogens have been shown to attenuate the cardiovascular benefits of estrogen, and this has been the subject of considerable debate.
Prevention has long been the holy grail of breast cancer research. The significant reduction in breast cancer risk afforded by a full-term pregnancy early in life suggests the great potential of preventive strategies.
In the first year after a postmenopausal women discontinues hormone therapy, her risk for cardiovascular mortality is higher than if she had continued the therapy, according to an observational study.
A dispute has raged for 70 years as to whether or not maturing women should replace their sex hormones. The age-reversal impact of hormone replacement is quite noticeable.
There’s a lot of confusion out there when it comes to the topic of progesterone and breast cancer. Many women worry when they hear that their breast cancer is both ER+ and PR+, believing this to be “double trouble”. It is time to set the record straight.
Premarin (Wyeth-Ayerst) is the estrogen replacement treatment of choice and continues to be one of the most widely dispensed prescriptions in North America.
A double-blind trial that evaluated the effects of coenzyme Q10 (CoQ10) supplementation among women with polycystic ovary syndrome (PCOS) resulted in lower glucose, insulin, insulin resistance, and total and low density lipoprotein (LDL) cholesterol in those who received the supplement compared with a placebo group.
Hormone Replacement Therapy (HRT) has long been a controversial treatment for symptoms of menopause, but recent data might reveal its true benefits.
There has been a tsunami-like surge in the use of compounded hormones by newly perimenopausal women, according to a survey conducted by the North American Menopause Society (NAMS).
